MEDICATION, NOCTURNAL DIPPING PROFILE AND HYPERTENSIVE EMERGENCY
نویسندگان
چکیده
Introduction: The aim of this study was to analyze the medication used by patients with hypertensive crisis (blood pressure above 180/120mmHg) and its impact on main risk factors for emergency development. Methods: A total 233 (108 male, 125 female), 184 had urgency/ 53 (54.44% /50.95% in women) at Emergency department during 11 months. Patients were divided five age groups as decades starting from 40 (mean 65.85 years) a ten depending which type they using (ACEi, ARB, BB, CCB, diuretics, moxonidine, their combinations). Results: By antihypertensive monotherapy percentage emergencies 100.00%, 50.00%, 41.66%, 33.33%, 21.05%. Using ACEi + CCB diuretic significantly decreased number 0%, 18.47%, 21.05%, 25.00%, 33.33%; but adding beta blocker additionally diminished risk. Overall no (22.75%) 68 smokers (29.18%, 63.23% male) 36 (52.94% smokers). biggest non-dippers found who took ARBs, diuretics and/or smallest shown combination moxonidine (-20.07%). 22.02% (-54.67% nonsmokers). Odds ratio getting case patient non-dipper profile 4.18 (CI 1.02 – 18.89, p < 0.05). taking different (or none) did not have increased chance development (OR 1.21, = NS). We didn’t find any differences non-dipping incidence between genders (72.12% males, 72.83% females). Conclusion: Combinations all showed benefit over monotherapy. Higher 24-hour nighttime blood (non-dipping profile) associated greater change developing emergency.
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ژورنال
عنوان ژورنال: Revista ciencia médica
سال: 2022
ISSN: ['2220-2234', '1817-7433']
DOI: https://doi.org/10.51581/rccm.v25i1.465